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KMID : 1149020210230010037
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Journal of Korean Society of Computed Tomographic Technology
2021 Volume.23 No. 1 p.37 ~ p.46
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A Study on the Effect of Heart rate based Left Ventricular Global Function on the Time of Contrast Enhancement
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Seo Choong-Beom
Nam Tae-Hyun
Chae Hee-Chang
Kim Seong-Gwan
Seo Eun-Hee
Dae Chang-Min
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Abstract
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Purpose: It was intended to find out whether a constant correlation between the cardiac function and the contrast enhancement time was established and to obtain the estimated contrast enhancement time according to the cardiac function.
Material and Method: A phantom study was preceded to verify the adequacy of cardiac function evaluation. A retrospective study of 273 patients who performed CCTA was conducted to measure cardiac function and compare contrast enhancement time. Cardiac functional indicators used Heart Rate, Cardiac Output, Cardiac Index, Cardiac Index per second, Left Ventricular Ejection Fraction, and Left Ventricular Ejection Fraction per second based on heart rate.
Results: In the phantom study, the change rate of volume measured by ECG based tube current modulation was less than 0.1%. A retrospective study found the Left Ventricular Ejection Fraction per second based on heart rate showed a clear negative correlation with contrast enhancement time (P<0.01) and the highest reliability. Through this, the expected contrast enhancement time was derived from the regression equation in correlation with the contrast enhancement time, but the regression equation was not established.
Conclusions: The contrast enhancement time and Left Ventricular Ejection Fraction per second based on heart rate were clearly correlated, but the contrast enhancement time, which consists of the complex interactions of various factors, could not be predicted by the cardiac function alone. If the study of the effects of circulating factors in the body continues, it is believed that contrast enhanced CT based on the patient's condition will be possible.
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KEYWORD
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Contrast Enhancement, Heart Rate, Cardiac Output, Cardiac Index, Left Ventricle Ejection Fraction
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